This roundtable discussion on Managing Critically Ill Patients with Continuous Kidney Replacement Therapies (CKRT) includes a lively discussion about the current global landscape of critical care, followed by typical CKRT modalities, parameters, and guidelines applied in the critical care setting, and finally applications of CKRT. In between speaker talks were two abbreviated roundtable/Q&A sessions which were followed by a comprehensive roundtable discussion at the end.