{"id":2763,"date":"2020-03-18T21:16:14","date_gmt":"2020-03-19T02:16:14","guid":{"rendered":"https:\/\/staging.advancedrenaleducation.com\/wparep\/?post_type=article&p=1006"},"modified":"2025-05-22T13:13:13","modified_gmt":"2025-05-22T18:13:13","slug":"time-versus-dialysis-free-interval","status":"publish","type":"article","link":"https:\/\/staging.advancedrenaleducation.com\/wparep\/asiapacific\/article\/time-versus-dialysis-free-interval\/","title":{"rendered":"Time Versus Dialysis-Free Interval"},"content":{"rendered":"

In an attempt to conform clinical outcomes to theoretical constructs, we have analyzed the spectrum of HD prescriptions according to interdialytic intervals. The following figure shows the shortest and longest dialysis-free intervals for various prescriptions.<\/p>\n

 <\/p>\n

\"\"<\/p>\n

Cumulative weekly dialysis time versus dialysis-free interval for various prescriptions<\/strong><\/p>\n

It is evident that there was no correlation between clinical outcomes (such as those of Tassin and Lecce) with total weekly dialysis time.\u00a0 While Tassin provides twice as many dialysis hours as conventional thrice weekly HD, it only reduces the longest interdialytic interval by 6% (from 68 to 48 hours).\u00a0 The long interdialytic interval can only be significantly reduced by increasing frequency beyond thrice weekly.\u00a0 There is little difference between the longest intervals for the various \u201cincreased frequency schedules\u201d (range 40-45.5 hrs) despite a total dialysis time range from 14 to 48 hours.\u00a0 Increasing the frequency beyond 3.5 times per week has little additional effect on the long interdialytic interval.\u00a0 The long and short interdialytic intervals of HD3.5<\/sub> are identical.\u00a0 This combination is associated with the best clinical outcomes adjusted for total length of dialysis.<\/p>\n

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